Le trailer ye-documentary ifilimu Ubufakazi Bokulimaza ifaka isiguli esine-MS esixoxa ngesixhumanisi sayo nokugcwaliswa kwayo kwamazinyo kwe-amalgam mercury.

I-Multiple Sclerosis & Ukuvezwa kweMercury; Isifinyezo Nezinkomba

i-mercury yamazinyo ne-multiple sclerosisI-Multiple sclerosis ("MS") yaqala ukubonakala ngekhulu leshumi nesishiyagalolunye ngesikhathi lapho ukuhlanganiswa kwe-amalgam kwaqala ukusetshenziswa kakhulu. Ubufakazi be-anecdotal obungashicilelwe buveze ukuthi inani elikhulu, kepha ngokuqinisekile akulona lonke, izisulu ze-MS ezinokugcwaliswa kwazo kwe-mercury / silver okususwe ukuxazululwa (ukuxolelwa okuzenzakalelayo) noma zithuthuke kancane kancane. Lobu bufakazi bendatshana busekelwa yizifundo ezishicilelwe phakathi neminyaka engama-50 edlule.

Isibonelo, emsebenzini owashicilelwa ngo-1966, u-Baasch waphetha ngokuthi i-multiple sclerosis kwakuyindlela yabantu abadala ye-acrodynia (isifo esibomvana) kanye ne-neuro-allergen reaction eyabangela, ezimweni eziningi, i-mercury evela ekugcwalisweni kwe-amalgam.1  UBaasch ubike amacala athile futhi wacaphuna izifundo eziqhubekayo ezikhombisa ukumiswa kokuqhubeka nokwenza ngcono ukuxazululwa kwe-MS ngemuva kokususwa kokugcwaliswa kwe-amalgam.

Ocwaningweni oluningiliziwe olushicilelwe ngo-1978, uCraelius ukhombise ukuhlangana okuqinile (P <0.001) phakathi kwamanani okufa kwe-MS kanye nama-caries amazinyo.2  Imininingwane ikhombise ukungenzeki ukuthi lokhu kuhlangana kungenxa yengozi. Izindlela eziningi zokudla zakhishwa ngaphandle njengezimbangela ezinomthelela.

I-hypothesis eyethulwe yi-TH Ingalls, MD, ngo-1983 yaphakamisa ukuthi ama-seepage amancane, abuyiselwe emuva e-mercury avela emiseleni yezimpande noma ukugcwaliswa kwe-amalgam kungaholela ku-MS eminyakeni yobudala obuphakathi.3  Ubuye wahlola kabusha imininingwane ebanzi yezifo ezibonisa ukuhlangana okuhlelekile phakathi kwamazinga okufa avela ku-MS nezinombolo zamazinyo abolile, alahlekile, futhi agcwalisiwe. Kucwaningo olushicilelwe ngo-1986, u-Ingalls uphakamise ukuthi abaphenyi abafunda ngezimbangela ze-MS kufanele bahlole ngokucophelela umlando wamazinyo weziguli.4

Ezinye izifundo zaqhubeka nokwakha ukuxhumana okukhona phakathi kwe-MS ne-mercury. Isibonelo, ucwaningo olwenziwe ngu-Ahlrot-Westerlund kusuka ngo-1987 luthole ukuthi iziguli ze-MS zinezikhathi eziphindwe kasishiyagalombili ezingeni elijwayelekile le-mercury emithanjeni yazo yomgogodla wobuchopho uma kuqhathaniswa nezilawuli ezinempilo ngokwemizwa.5

Ngaphezu kwalokho, abacwaningi uSiblerud noKienholz baseRocky Mountain Research Institute, Inc., baphenye umbono wokuthi i-mercury evela ekugcwalisweni kwamazinyo yamazinyo ihlobene ne-MS emsebenzini owashicilelwa ngo-1994.6  Iqhathanise ukutholakala kwegazi phakathi kwezihloko ze-MS ezisuswe amalamal azo kanye nezifundo ze-MS ngama-amalgams:

Izifundo ze-MS ezinama-amalgamu zitholwe zinamazinga aphansi kakhulu wamaseli abomvu egazi, i-hemoglobin, ne-hematocrit uma kuqhathaniswa nezifundo ze-MS ngokususwa kwe-amalgam. Amazinga e-Thyroxine nawo abephansi kakhulu eqenjini le-MS amalgam, futhi ayenamazinga aphansi kakhulu wamaseli we-T Lymphocyte ne-T-8 (CD8) wokucindezela amaseli. Iqembu le-MS amalgam laline-nitrogen yegazi ephakeme kakhulu ne-serum ephansi ye-IgG. Izinwele ze-mercury zaziphakeme kakhulu ezifundweni ze-MS uma kuqhathaniswa neqembu elingelona ele-MS. Uhlu lwemibuzo lwezempilo luthole ukuthi izifundo ze-MS ezinama-amalgamu zinokukhula okuthe xaxa (33.7%) ezinyangeni eziyi-12 ezedlule uma kuqhathaniswa namavolontiya e-MS asuswa nge-amalgam. 7

Indima ye-myelin, into esiza ubuchopho ukuthumela imiyalezo emzimbeni, iyinto ebalulekile yocwaningo lwe-MS, kanti iMELISA Foundation isungule lokho abakholelwa ukuthi kuyimpumelelo ekuqondeni i-MS ngokubona ukuxhumana phakathi kokungezwani komzimba nensimbi nokuguguleka kwe-myelin.  Kucwaningo olushicilelwe ngo-1999, UStejskal noStejskal baphawula ukuthi ukusabela kokuzwela ngokweqile kubangelwa izinhlayiya zensimbi ezingena emzimbeni womuntu ongazwani nensimbi okukhulunywa ngayo.8  Lezi zinhlayiya bese zibopha i-myelin, zishintshe kancane ukwakheka kwamaprotheni. Kubantu abanokuzwela, isakhiwo esisha (i-myelin plus metal particle) sikhonjwa ngamanga njengomhlaseli wangaphandle futhi sihlaselwa (impendulo yokuzimela). Icala libukeka njenge "myelin plaque" ebuchosheni, ejwayelekile ezigulini ezine-MS. Amapuleti anjalo angaba ngumphumela wokungezwani komzimba nensimbi. Ngokushesha iMELISA Foundation yaqala ukubhala phansi ukuthi iziguli ezinezinkinga zokuzivikela komzimba zenza ingxenye ethile, futhi kwezinye izimo, zilulame ngokugcwele ngokususa umthombo wensimbi — okuvame ukugcwaliswa ngamazinyo.9

Ucwaningo lwamaqembu abuyela emuva nguBates et al. eyashicilelwa ngo-2004 ifaka phakathi ukuhlola amarekhodi okwelashwa kwabantu abayi-20,000 XNUMX embuthweni Wezokuvikela waseNew Zealand (NZDF).10  Abaphenyi bahlose ukuhlola ukuxhumana okungahle kube khona phakathi kokuhlanganiswa kwamazinyo nemiphumela yezempilo, futhi abakutholile kwaholela ekubeni baphakamise inhlangano "eqinile" phakathi kwe-MS nokuvezwa kwe-amalgam yamazinyo. Ngaphezu kwalokho, izifundo ezintathu ezishicilelwe ngaphambili zokulawulwa kwamacala e-MS eziphethe ngokuthi bekungekho ukuzibandakanya okukhulu nokufakwa kwamazinyo kwe-amalgam mercury11 12 13 zikhonjwe nguBates et al. njengokukhawulelwa okuhlukahlukene. Ngokuqondile kakhulu, uBates nozakwabo baqaphele ukuthi isifundo esisodwa kuphela kulezi ezintathu sisebenzise amacala ezehlakalo kanye namarekhodi wamazinyo, nokuthi isifundo esifanayo empeleni sikhiqize izilinganiso eziphezulu zobungozi zenani elikhulu lokugcwaliswa kwe-amalgam mercury.14

Ukubuyekezwa okuhlelekile kwezincwadi ezimayelana nokuhlanganiswa kwamazinyo kanye ne-multiple sclerosis kwenziwa ngabaphenyi baseCanada futhi kwashicilelwa ngo-2007.15  Ngenkathi u-Aminzadeh et al. babike ukuthi ubungozi bezinga le-MS phakathi kwabaphathi be-amalgam buyafana, baphakamisa ukuthi kube ukwanda okuncane futhi okungabalulekanga ngokwezibalo. Kodwa-ke, bakhulume ngokulinganiselwa komsebenzi wabo futhi bancoma nokuthi izifundo zesikhathi esizayo kufanele zinake ezinye izinto ezinjengosayizi we-amalgam, indawo engaphezulu, nobude besikhathi sokuchayeka lapho kuqhubeka nokuhlola noma yikuphi ukuxhumana phakathi kwe-amalgam yamazinyo ne-MS.

Iziguli ezingamashumi ayisikhombisa nane ezine-MS kanye namavolontiya angamashumi ayisikhombisa nane anempilo ayeyizihloko zesifundo se-Iranian sika-Attar et al. eshicilelwe ngo-2011.16  Abaphenyi bathole ukuthi izinga le-serum mercury ezigulini ze-MS laliphezulu kakhulu kunezilawuli. Baphakamise ukuthi amazinga aphezulu e-mercury ku-serum angaba yingxenye yokuthambekela kwe-multiple sclerosis.

Ngo-2014, uRoger Pamphlett waseYunivesithi yaseSydney e-Australia kwashicilelwa imicabango yakhe yezokwelapha ehlanganisa izinto ezinobuthi zemvelo, kufaka phakathi i-mercury, nezinkinga zesistimu yezinzwa ephakathi.17  Ngemuva kokuchaza ukuvezwa yizidakamizwa ezinobuthi kanye nomthelela emzimbeni, uphakamise wathi: “Ukungasebenzi kahle kwe-noradrenaline kuthinta amaseli amaningi e-CNS futhi kungadala inani le-neurodegenerative (i-Alzheimer's, i-Parkinson's kanye ne-motor neuron disease), idiliza (i-multiple sclerosis), nezimo zengqondo (ukucindezeleka okukhulu kanye nokuphazamiseka kwengqondo okuguquguqukayo) izimo. ”18

Ucwaningo olushicilelwe ngo-2016 lukhombise ukuthi uPhamfulethi wayeqoqe ubufakazi bokuxhasa umbono wakhe. Yena nozakwabo bafunda amasampula omgogodla kubantu abangu-50 abaneminyaka engu-1-95 ubudala.19  Bathola ukuthi ama-33% alabo abaneminyaka engu-61-95 abanensimbi esindayo ekhona kuma-interneuron abo omgogodla (kanti abancane abakwenzile). Ucwaningo lubaholele ekutheni baphethe ngokuthi: "Ukulimala kwama-interneuron avimbelayo kusuka ezinsimbini ezinobuthi empilweni yakamuva kungaholela ekulimaleni kwe-excitotoxic kuma-motoneuron futhi kungahle kube nokulimala noma ukulahleka kwe-motoneuron ezimeni ezinjenge-ALS / MND, i-multiple sclerosis, i-sarcopenia kanye nethole."20

Olunye ucwaningo olushicilelwe ngo-2016, evela kubacwaningi base-University of North Carolina, i-Centers for Disease Control and Prevention, neDuke University, ngokufanayo ihlolisise ukuxhumana okungaba khona phakathi kwezinsimbi ezisindayo ne-multiple sclerosis.21  Abantu abangama-217 abanezilawuli ze-MS nezingama-496 bafakiwe ocwaningweni lokulawulwa kwamacala olwenziwe ngabantu, olwenzelwe ukuhlola ubudlelwano phakathi kokuchayeka ekuholeni, i-mercury, kanye ne-solvents kanye nama-polymorphisms angama-58 e-nucleotide owodwa kuzakhi zofuzo ezihlobene ne-MS. UNapier et al. bathole ukuthi abantu abane-MS babenamathuba amaningi kunezilawuli zokubika ukuvezwa kokuhola kanye ne-mercury.

Kubalulekile futhi ukuqaphela ukuthi imilando eminingana yamacala eshicilelwe eminyakeni engama-25 edlule, ngaphezu kocwaningo oluthile okukhulunywe ngalo ngenhla, ibhale ukuthi kungenzeka ukuthi iziguli ze-MS zithole amazinga ahlukahlukene okuthuthuka kwezempilo ngemuva kokususwa kokugcwaliswa kwazo kwe-amalgam. Ucwaningo olwenziwe nguRedhe noPleva olushicilelwe ngo-1993 lwaqokomisa izibonelo ezimbili ezivela emacaleni angaphezu kwezi-100 eziguli ezihlola imiphumela ye-immunological ye-dent amalgam.22  Baphakamise ukuthi ukususwa kwe-amalgam kuveza imiphumela enenzuzo kwezinye izimo ze-MS. Njengesinye isibonelo, isifundo esenziwe nguHuggins noLevy esashicilelwa ngo-1998 sakhombisa ukuthi ukususa ama-amalgams wamazinyo, lapho kwenziwa ngeminye imishanguzo yokwelashwa, kwaguqula izici ze-photolabeling zamaphrotheni e-cerebrospinal fluid kubantu abane-MS.23

Ezinye izibonelo zinikeza nobufakazi bezinzuzo ezingase zibe khona zokususwa kwe-amalgam ezigulini ze-MS. Ucwaningo oluvela eMELISA Foundation olushicilelwe ngo-2004 kuhlolwe imiphumela yezempilo yokususwa kwe-amalgam ezigulini ze-mercury-aleji ezinokuzivikela komzimba, futhi izinga eliphakeme kakhulu lokuthuthuka lenzeke ezigulini ezine-MS.24  Ngaphezu kwalokho, umlando wamacala owashicilelwa ngo-2013 usuka kubacwaningi base-Italiya wabhala ukuthi isiguli esine-MS esasifakelwe imercury sasuswa sabe sesithola ukwelashwa kwe-chelation (uhlobo oluthile lokukhishwa kobuthi emzimbeni) sathuthuka.25  Abaphenyi, omunye wabo ohlangene noMnyango Wezempilo e-Italy, babhala ukuthi ubufakazi obethulwayo buvame “ukuqinisa umbono we-TMP [ushevu wensimbi onobuthi] njengesiqalo sezemvelo noma se-iatrogenic se-MS, ikakhulukazi lapho ukungasebenzi kahle kwenhlanzeko impande. ” 26

Yize kudingeka olunye ucwaningo ukuthola ubungako obugcwele bobudlelwano phakathi kwe-mercury ne-MS, izincwadi zesayensi ezishicilelwe eminyakeni engama-50 edlule ziyaqhubeka nokusikisela ukuthi ukuvezwa kwe-mercury kusuka kuma-amalgams wamazinyo, kanye nanoma ikuphi okunye ukuvezwa okungapheli kwama-mercury aphansi, kufanele unikezwe ukucatshangelwa okukhulu ngendima engaba khona ku-etiology ye-MS. Kumele futhi kukhunjulwe ukuthi okunye ukuvezwa okunobuthi kungenzeka kudlale izindima ezifanayo, okusiza ukuchaza ukuthi kungani ezinye iziguli ze-MS zingenayo i-mercury amalgam yamazinyo okugcwaliswa noma okunye ukuvezwa kwe-mercury okwaziwayo. Isibonelo, ucwaningo olushicilelwe ngo-2016 ngabaphenyi baseTaiwan baxhumanisa i-MS ukuhola ukuvezwa emhlabathini.27

Okunye futhi okufanele kukhunjulwe ukuthi kukonke, ucwaningo lwamanje kakhulu lukhombisa ukuthi ukubangelwa yi-MS kusebenza kahle kakhulu. Ngakho-ke, i-mercury ingabhekwa njengesici esisodwa nje esingaba khona kulesi sifo, nokunye ukuvezwa okunobuthi, ukuhlukahluka kofuzo, ukuba khona kokungezwani komzimba nensimbi, kanye nezimo eziningi ezengeziwe kudlala indima enkulu naku-MS.

IZINDAWO ZOLWAZI

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  1. I-Aminzadeh KK, i-Etminan M. Dental amalgam kanye ne-multiple sclerosis: Ukubuyekezwa okuhlelekile nokuhlaziywa kwemeta. Ijenali Yezempilo Yomphakathi Amazinyo. 2007 uJan 1; 67 (1): 64-6.
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I-IAOMT inezinsizakusebenza eziningi ezengeziwe ezihlobene nalesi sihloko:

Dental Mercury Article Ababhali

( Umfundisi, Umdidiyeli wefilimu, iPhilanthropist )

UDkt. David Kennedy wenza udokotela wamazinyo iminyaka engaphezu kwengu-30 futhi wathatha umhlalaphansi emsebenzini wokwelapha ngo-2000. UnguMongameli Odlule we-IAOMT futhi useke wafundisa odokotela bamazinyo nabanye ochwepheshe bezempilo emhlabeni wonke ngezindaba zempilo yamazinyo, ubungozi be-mercury, kanye ne-fluoride. UDkt. Kennedy waziwa emhlabeni wonke njengommeli wamanzi okuphuza aphephile, udokotela wamazinyo webhayoloji futhi ungumholi owaziwayo emkhakheni wokuvimbela amazinyo. UDkt. Kennedy ungumbhali nomqondisi ophumelele indondo yefilimu i-Fluoridegate.

UDkt. Griffin Cole, i-MIAOMT yathola i-Mastership yakhe ku-International Academy of Oral Medicine kanye ne-Toxicology ngo-2013 futhi yabhala Ibhukwana le-Academy's Fluoridation Brochure kanye nokubuyekezwa okusemthethweni kweSayensi mayelana nokusetshenziswa kwe-Ozone ekwelapheni kwezimpande. UnguMongameli wesikhathi esidlule we-IAOMT futhi usebenza Ebhodini Labaqondisi, Ikomidi Lokuqondisa, Ikomidi Le-Fluoride, IKomidi Lenkomfa futhi unguMqondisi Wezifundo Eziyisisekelo.

Chofoza lapha ukuthola inguqulo ye-pdf yale dokhumenti enezinkomba zesayensi
Isiguli esigulayo embhedeni nodokotela sixoxa ngokusabela nemiphumela engemihle ngenxa yobuthi be-mercury
Ukugcwaliswa kweMercury: Imiphumela Yokuphathwa Kwamazinyo e-Amalgam kanye Nemiphumela

Ukuphendula kanye nemiphumela engemihle yokugcwaliswa kwamazinyo kwe-amalgam mercury kusekelwe ezintweni eziningi eziyingozi.

Ukugcwaliswa kweMercury: Imiphumela Yokuphathwa Kwamazinyo e-Amalgam kanye Nemiphumela
Izimpawu Zobuthi beMercury Nokugcwaliswa Kwe-Amalgam Yamazinyo

Ukugcwaliswa kwamazinyo kwe-amalgam mercury kuyaqhubeka kukhulula umusi futhi kungaveza izimpawu eziningi zobuthi be-mercury.

Izimpawu Zobuthi beMercury Nokugcwaliswa Kwe-Amalgam Yamazinyo
Ukubuyekezwa Okuphelele Kwemiphumela YeMercury Ekugcwalisweni Kwamazinyo e-Amalgam

Lokhu kubuyekezwa okuningiliziwe kwamakhasi angama-26 avela ku-IAOMT kufaka phakathi ucwaningo mayelana nobungozi empilweni yomuntu nasemvelweni kusuka kwi-mercury ekugcwalisweni kwamazinyo e-amalgam.

Ukubuyekezwa Okuphelele kwe-IAOMT nge-Dental Amalgam

Yabelana ngale ndatshana ezinkundleni zokuxhumana